Best Sega Genesis Game??

I personally don't see any game as the best. There are lots of great ones out there, including:

*Comix Zone
*Shining Force
*Sonic 1-3 & Knuckles
*Vectorman 1-2
*Shinobi III

If you've got a PS2 or PSP, go pick up that Sega Genesis Collection, it's worth the money, and you've got some great games. 

grr...i hate "best" questions....i'd say street fighter 2 (depending on the version) although the snes versions were better...

i'd look into ecco the dolphin, kid chameleon, sword of vermillion, sonic (or course), toejam & earl to name a few that come apparent